Cocaine

Permanent damage to blood vessels

High BP leading to strokes, heart attacks and even death

Liver, lung and kidney damage

Nose tissue damage

Respiratory failure if smoked

Risk of HIV and Hepatitis if injected

Malnutrition and severe weightloss

Hallucinations

Sexual problems including infertility

Irritability and mood swings

Increased risk of irrational and destructive behaviour

Delirium or psychois

Severe depression

Tolerance and addiction (even after a single use)